Ultrahigh pressure structural changes in a 60 mol. % Al2O3–40 mol. % SiO2 glass

Mol # 61788

The concept of selective receptor modulators has been established for the nuclear steroid hormone receptors. Such selective modulators have been utilized therapeutically with great success in the treatment of cancer. However, this concept has not been examined with regard to the aryl hydrocarbon receptor (AHR) because of the latent toxicity commonly associated with AHR activation. AHR-mediated ...

Mol Med Activities

Mol 12443 1

1 Investigation of cooperativity in the binding of ligands to the D 2 dopamine receptor. Abstract The D 2 dopamine receptor exists as dimers or as higher order oligomers, based on data from physical experiments. In this study we have sought evidence that this oligomerisation leads to cooperativity by examining the binding of three radioligands ([ 3 H]nemonapride, [ 3 H]raclopride, [ 3 H]spipero...

Revi Mol Hai

acrjourna understanding of the anatomy and development of fetal and adult hair follicles and the molecular of the major embryonic pathways that regulate the hair follicle have led to exciting discoveries rning the development of basal cell carcinoma (BCC). These studies have shed light on the major f Sonic hedgehog (Shh) signaling and its interactions with the insulin-like growth factor (IGF) a...

Mol #71308 Mol #71308 2 Running Title: Abl Kinases Regulate Nicotinic Signaling in Autonomic Neurons Mol #71308 3

1 Title: Abelson family tyrosine kinases regulate the function of nicotinic acetylcholine receptors and nicotinic synapses on autonomic neurons. Abbreviations: Abelson family tyrosine kinase (AFK), Abelson family tyrosine kinase 1 (Abl1, c-Abl), Abelson family tyrosine kinase 2 (Abl2, Arg), non receptor tyrosine kinase (NRTK), Src family tyrosine kinase (SFK), postsynaptic density (PSD), nicoti...